Quit smoking without nicotine

Acetium lozenge – quit smoking without nicotine

There are a variety of ways to help quit smoking, but many of the available products have adverse effects or cause dependency.

The latest method to combat nicotine addiction is the Acetium lozenge, developed and made in Finland and based on the natural amino acid L-cysteine.

Using Acetium is as simple as taking one lozenge each time you smoke a cigarette.

The success of your efforts to quit smoking is tied to your own motivation. To achieve the best results, the lozenges should be taken regularly for 3-6 months, on average. In other words, be patient even as change may not happen overnight!

A Finnish innovation

Developed and manufactured in Finland, the Acetium lozenge is free of the side effects of conventional smoking cessation methods, such as nicotine dependency or possible adverse effects of medication.

How does Acetium work?

The effectiveness of Acetium lozenges in smoking intervention has been evaluated in two clinical trials (1, 2). Regular use of the lozenge during smoking increases the likelihood of quitting by a factor of 1.5 compared to a placebo (2).

Acetium lozenges contain L-cysteine, a natural amino acid that efficiently binds acetaldehyde dissolved in saliva from cigarette smoke and converts it into a harmless compound (3).

Acetium® lozenges contain no harmful ingredients. In addition to L-cysteine, the lozenges contain a small amount of xylitol to reduce the production of acetaldehyde by bacteria in the mouth and improve oral hygiene.

What is acetaldehyde?

Normal saliva does not contain acetaldehyde (3). Acetaldehyde is a carcinogen (4) and one of the harmful substances in tobacco smoke. The Acetium lozenge removes up to 90% of smoke-derived acetaldehyde in saliva.

An effective way to quit smoking without nicotine dependency

The latest double-blind trial (2) was participated in by 2,000 smokers, and its results confirmed those of the previous trial (1). The effectiveness of the Acetium lozenge as a smoking cessation product was clearly superior to that of the placebo. Smokers who used Acetium were more likely to quit smoking than those in the placebo group by a factor of 1.5.

According to smokers who participated in the clinical trial, the use of Acetium results in a reduction of the pleasure gained by smoking and a change in the taste of cigarettes, which facilitate the cessation of smoking (2).

“The results of the trial represent a significant breakthrough in the development of smoking cessation methods. The latest comparative trial accurately repeats the results of the previous trial (1), thereby confirming that the Acetium lozenge is a significantly more effective aid in smoking cessation compared with the placebo,” says Professor Kari Syrjänen, Chief Medical Director at Biohit Oyj.


1. Syrjänen K et al. Elimination of cigarette smoke-derived acetaldehyde in saliva by slow-release L-cysteine lozenge is an effective new method to assist smoking cessation. A randomised, double-blind, placebo-controlled intervention. Anticancer Res.  2016;36:2297-2306. 

2. Syrjänen K et al. Slow-release L-cysteine (Acetium) lozenge is an effective new method in smoking cessation. A randomized, double-blind, placebo-controlled intervention. Anticancer Res 2017;37:3639-3648.

3. Salaspuro VJ et al. Eliminating carcinogenic acetaldehyde by cysteine from saliva during smoking. Cancer Epid Biomark Prev 2006;15:146-149.

4. Secretan B et al. WHO International Agency for Research on Cancer Monograph Working Group. A review of human carcinogens- Part E: tobacco, areca nut, alcohol, coal smoke, and salted fish. Lancet Oncol 10:1033-1034.